Immune mediation
نویسندگان
چکیده
منابع مشابه
mediation: R Package for Causal Mediation Analysis
In this paper, we describe the R package mediation for conducting causal mediation analysis in applied empirical research. In many scientific disciplines, the goal of researchers is not only estimating causal effects of a treatment but also understanding the process in which the treatment causally affects the outcome. Causal mediation analysis is frequently used to assess potential causal mecha...
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Heterologous expression of Toll-like receptor (TLR)2 and CD14 in Chinese hamster ovary fibroblasts was reported to confer responsiveness to pneumococcal peptidoglycan. The present study characterized the role of TLR2 in the host immune response and clinical course of pneumococcal meningitis. Pneumococcal infection of mice caused a significant increase in brain TLR2 mRNA expression at both 4 and...
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Background. The relation between the sympathetic nervous system and the immune system has not been fully defined. Recent investigations have suggested an adrenergically driven efflux of specific P2-receptorrich lymphocyte subsets into the circulation with either exercise or infusion of exogenous catecholamines. Methods and Results. To determine whether acute sympathetic stimulation mediates imm...
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Animals living in temporally dynamic environments experience variation in resource availability, climate and threat of infection over the course of the year. Thus, to survive and reproduce successfully, these organisms must allocate resources among competing physiological systems in such a way as to maximize fitness in changing environments. Here, we review evidence supporting the hypothesis th...
متن کاملSympathetic and immune interactions during dynamic exercise. Mediation via a beta 2-adrenergic-dependent mechanism.
BACKGROUND The relation between the sympathetic nervous system and the immune system has not been fully defined. Recent investigations have suggested an adrenergically driven efflux of specific beta 2-receptor-rich lymphocyte subsets into the circulation with either exercise or infusion of exogenous catecholamines. METHODS AND RESULTS To determine whether acute sympathetic stimulation mediate...
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ژورنال
عنوان ژورنال: Cell
سال: 1979
ISSN: 0092-8674
DOI: 10.1016/0092-8674(79)90250-2